On your way up stop by the town of Lone Butte, it is by 93 Mile House on BC Prov Hwy 24. There is a small cafe where the hostess seats you, takes your order and cooks your meal-it is a one woman show. We also stopped by the sporting goods store just down the street to get our fishing licenses and some pointers on the HOT fishing spots.

Traveling in this area in a bit rough on the vehicle, almost all the roads are dirt/gravel. I would suggest taking a truck with 4 wheel drive. I have had to use 4 wheel a few times after a big rain storm, the roads where 4 inches of sticky mud, or to navigate down to some of the lake shorelines

Jump back on the BC Prov Hwy 97 and head north, once in 100 Mile House you can get any supplies you are going to need-grocery stores, sporting goods, gas stations, small boutiques, etc. We usually head north out of 100 Mile House towards Forest Grove, and continue on the south side of Canim Lake. Check your fishing regulations to verify what is open and what restrictions are in place (single barb less hooks) because fishing is awesome almost everywhere. We usually stop at just about every stream, river or lake- although now we know which ones we have better luck in. For instance Kanim River, Lorine Lake, Cougar Lake, Bowers Lake and countless others.

We usually head into Cougar Lake, there is a great camping spot near the lake and there are usually some moose that come out into the lake while your fishing or just relaxing. From there you can continue a bit and go in the back way to Bowers Lake.

We usually head south in the backcountry wandering around. Although we have been up past 150 Mile House and south to Kamloops on the east and west sides of the highway. I do like the west side- there are less people and the fishing is great. Take a camera-there are numerous moose, bear, deer and many others.

Fishing-- The fishing is awesome, there are so many varieties of fish I could not believe it. Take a raft or a canoe the lakes are big. There are few lakes you can hike into near Bowers Lake.

 Do it again? Any time I have a chance

Links:

British Columbia Adventures 
100 Mile House and the South Cariboo Area
Map of the South Cariboo